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The New England Journal of Medicine: Research & Review Articles on Disease & Clinical Practice logo-32 logo-40 logo-60 New England Journal of Medicine NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group information and services. NEJM Journal Watch Concise summaries and expert physician commentary that busy clinicians need to enhance patient care. NEJM Knowledge + The most effective and engaging way for clinicians to learn, improve their practice, and prepare for board exams. NEJM Catalyst NEW! Peer-reviewed journal featuring in-depth articles to accelerate the transformation of health care delivery. NEJM Resident 360 Information, resources, and support needed to approach rotations - and life as a resident. NEJM Career Center Valuable tools for building a rewarding career in health care. NEJM Library Hub Information and tools for librarians about site license offerings. NEJM 医学前沿 The authorized source of trusted medical research and education for the Chinese-language medical community. The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In Create Account Renew subscription Subscribe Stay connected to what's important in medical research and clinical practice Create Account Subscribe to the most trusted and influential source of medical knowledge Subscribe Already a subscriber? Renew or Sign in Subscribe or Renew Search site Keyword New England Journal of Medicine Search Home Specialties Specialties Selected specialties View all specialties Allergy/ Immunology Cardiology Dermatology Emergency Medicine Endocrinology Gastroenterology Genetics Geriatrics/ Aging Hematology/ Oncology Infectious Disease Nephrology Neurology/ Neurosurgery Obstetrics/ Gynecology Pediatrics Primary Care/ Hospitalist Psychiatry Pulmonary/ Critical Care Rheumatology Surgery View all specialties -- Cardiology -- Hematology/Oncology -- Infectious Disease Topics Topics Selected Topics View all topics Health Policy Medicine and Society Case Studies in Social Medicine Data Sharing Pain Management Frontiers in Medicine Coronavirus Climate Crisis and Health Zika Virus Ebola Virus E-Cigarettes and Vaping-Related Disease View all topics -- Health Policy -- Medicine and Society -- Pain Management -- Ebola Virus Multimedia Multimedia Selected Multimedia View all multimedia Audio Clinical Practice Audio Interviews Audio Summaries Image Challenge Images in Clinical Medicine Interactive Medical Cases Quick Takes Videos in Clinical Medicine Visual Abstracts View all multimedia Vaping and Vitamin E Acetate EVALI and Adolescent Vaping A Rapid Change in Pressure Focused Cardiac Ultrasonography Current Issue Current Issue Current Issue Current Issue February 20, 2020 Vol. 382 No. 8 Recent Issues February 13, 2020 Vol. 382 No. 7 February 6, 2020 Vol. 382 No. 6 January 30, 2020 Vol. 382 No. 5 Browse full issue index Browse recently published Browse full issue index Recently Published Articles Defining the Epidemiology of Covid-19 — Studies Needed M. Lipsitch et al. SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients L. Zou et al. Stalled Federal Efforts to End Surprise Billing — The Role of Private Equity E.C. Fuse Brown Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China S. Hoehl et al. Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients H.T. Olsen et al. Calming Down about Sedation in Critically Ill Patients C. Guérin Browse recently published Learning/CME Learning/CME View all learning/CME CME Case 6-2020: A 34-Year-Old Woman with Hyperglycemia Prevention of Falls in Community-Dwelling Older Adults Trial of Nemolizumab in Moderate-to-Severe Prurigo Nodularis Challenge Yourself Interactive Medical Cases Image Challenge Videos in Clinical Medicine View all learning/CME Other NEJM Group Learning Hand Hygiene Essential information students and residents need to approach residency with confidence: practical training information, career guidance, insightful discussions. Effective, adaptive learning that helps you prepare for certification, maintain competency, and sharpen clinical decision-making while earning CME and MOC. Author Center Subscribe or Renew Keyword Advanced Search Editorial February 14 NEJM Coronavirus Update Listen to an interview, recorded February 14, with editors Eric Rubin and Lindsey Baden on SARS-CoV-2 and Covid-19: redefining the disease. Jan 27 Audio Interview Coronavirus Outbreak Correspondence SARS-CoV-2 Viral Load in Upper Respiratory Specimens L. Zou and Others The authors report results of an analysis of nasal and throat swabs from 17 patients in Zhuhai, China, who had received a diagnosis of Covid-19. Higher viral loads soon after symptom onset indicate the need for isolation strategies different from those used for the earlier SARS epidemic. Feb 19 Original Article Brief Report First U.S. Confirmed Case of 2019-nCoV Infection M.L. Holshue and Others A healthy 35-year-old man who had visited Wuhan, China, presented with cough and fever that progressed to pneumonia. This report describes the diagnosis, clinical course, and management of the condition. The case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels. Jan 31 Perspective Defining the Epidemiology of Covid-19 M. Lipsitch, D.L. Swerdlow, and L. Finelli Experience with MERS, pandemic influenza, and other outbreaks has shown that as an epidemic evolves, we face an urgent need to expand public health activities in order to elucidate the epidemiology of the novel virus and characterize its potential impact. Feb 19 Correspondence A Thai Taxi Driver with Covid-19 W.A. Pongpirul and Others The authors describe a taxi driver in Thailand who was infected with the novel coronavirus, potentially from passengers who were tourists from China, in January 2020. The infection appeared not to have spread to the taxi driver’s family or other close contacts. Feb 12 Correspondence Coronavirus in Travelers Returning from China S. Hoehl and Others A group of 126 German nationals was evacuated from Wuhan to Frankfurt after screening for symptoms of Covid-19 and was to undergo a 14-day quarantine and additional screening in Frankfurt. The authors discovered evidence of SARS-CoV-2 infection in throat swabs from 2 evacuated persons who had passed the symptoms-based screening. Feb 18 Clinical Decisions Disclosure of Genetic Results of a Research Study A. Castellanos and Others This interactive feature about deidentified data in a nationwide genetic database offers a case vignette accompanied by essays that either support or discourage reidentifying the data and notifying participants who have actionable pathogenic mutations. Vote and comment. Feb 20 Recent Information on Coronavirus (Covid-19) Image of the Week Sarcoidal Reaction in a Tattoo — This 42-year-old man presented with numerous papules along tattoos that he had received 10 years earlier. Original Research Original Article Role of Vitamin E Acetate in EVALI B.C. Blount and Others In a study involving 51 patients with electronic-cigarette, or vaping, product use–associated lung injury in 16 states across the United States, vitamin E acetate was detected in samples of bronchoalveolar-lavage fluid from 94% of the patients but not in samples from a healthy comparator group. Feb 20 Editorial Cornering the Suspects in Vaping-Associated EVALI Special Report Vaping Syndromic Surveillance K.P. Hartnett and Others Increases in EVALI were identified in 2019. Using the National Syndromic Surveillance Program, which includes about 70% of U.S. EDs, researchers found a gradual increase in ED visits associated with shortness of breath and e-cigarette use from January 2017 th...

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